News

Functional Fluidics has partnered with Safi Biotherapeutics Inc to validate the quality and efficacy of Safi’s stem-cell-derived manufactured red blood cells (mRBCs) for sickle cell disease (SCD). This collaboration aims …

Pfizer has shared an update on its open-label extension study evaluating the long-term safety of inclacumab in individuals with sickle cell disease (SCD). This monoclonal antibody, administered intravenously every 12 …

The NIH/NHLBI/HEMATOLOGY BRANCH have signed an agreement with Vascarta, Inc to conduct a Phase 1 clinical trial of VAS-101 (Vasceptor®), a topical curcumin gel designed to reduce pain and inflammation …

Bristol Myers Squibb has reached a critical milestone in its ELEMENT-MDS Phase 3 trial, evaluating luspatercept versus epoetin alfa for treating anemia in adults with lower-risk myelodysplastic syndromes (MDS) who …

Cellarity has dosed the first participant in a Phase 1 trial for CLY-124, a groundbreaking oral therapy designed to treat sickle cell disease (SCD) by reactivating fetal hemoglobin (HbF) through …

New findings from the ongoing phase 2/3 trial of osivelotor (GBT021601) by Global Blood Therapeutics/Pfizer highlight its potential to improve red blood cell health in sickle cell patients. Presented at EHA …

Vascarta Inc.’s VAS-101 (Vasceptor), an innovative topical curcumin treatment, has just received Orphan Drug Designation from the FDA. This status could fast-track its development, offering hope for safer, more effective …

New findings from the RESPONSE trial confirm Novartis‘s ruxolitinib provides comprehensive benefits for polycythemia vera (PV) patients who don’t adequately respond to hydroxyurea. The oral JAK1/2 inhibitor not only maintains …

Sanofi has received FDA orphan drug designation for rilzabrutinib, an investigational oral BTK inhibitor, as a potential treatment to reduce vaso-occlusive crises in sickle cell disease (SCD). The therapy is …